Cognitive Support

Peptides explored for their potential effects on focus, memory, neuroprotection, and overall brain health.

13 peptides

Cognitive health is a growing area of interest in peptide research. Several compounds have been studied for their potential to enhance focus, support memory, protect neurons, and promote brain-derived neurotrophic factor (BDNF) production. The evidence ranges from well-studied compounds approved in other countries to very early-stage research molecules.

Peptides for Cognitive Support

Semax

Nootropic Peptide

Beginner

A synthetic peptide analog of ACTH(4-10) developed in Russia, studied for cognitive enhancement and neuroprotection.

Cognitive SupportNeuroprotectionFocus+1

EmergingModerate Data

Selank

Nootropic Peptide

Beginner

A synthetic peptide analog of tuftsin with anxiolytic and nootropic properties, developed in Russia.

AnxietyMoodCognitive Support+1

EmergingModerate Data

Dihexa

Angiotensin Analog

A potent angiotensin IV analog studied for cognitive enhancement and potential treatment of neurodegenerative conditions.

Cognitive SupportNeuroprotectionMemory+1

PreliminaryLimited Data

NA-Semax-Amidate

Nootropic Peptide

A chemically modified version of Semax designed for improved stability. No published clinical or preclinical data exists for this specific compound.

Cognitive SupportNeuroprotectionFocus+1

LimitedLimited Data

Humanin

Mitochondrial-Derived Peptide

A mitochondria-derived peptide with cytoprotective properties, studied for neuroprotection, metabolic regulation, and anti-aging effects.

NeuroprotectionLongevityMetabolic Health+1

EmergingLimited Data

VIP

Neuropeptide

A naturally occurring neuropeptide with anti-inflammatory, neuroprotective, and immune-modulating properties. Early clinical data exists for pulmonary hypertension; other therapeutic uses remain under investigation.

Anti-InflammatoryNeuroprotectionImmune Modulation+1

ModerateModerate Data

Cerebrolysin

Neurotrophic Peptide Complex

A porcine brain-derived peptide preparation with neurotrophic properties, approved in several countries for stroke recovery and cognitive disorders.

NeuroprotectionCognitive EnhancementStroke Recovery+1

StrongWell-Studied

Pinealon

Bioregulator Peptide

Beginner

A short tripeptide studied for neuroprotective and cognitive-enhancing properties, part of the Khavinson peptide bioregulator family.

NeuroprotectionCognitive EnhancementAnti-Aging+1

PreliminaryLimited Data

Cortagen

Bioregulator Peptide

A synthetic peptide bioregulator targeting brain cortex function, studied for cognitive enhancement and neuroprotection in aging.

Cognitive EnhancementNeuroprotectionBioregulator+1

PreliminaryLimited Data

N-Acetyl Selank Amidate

Nootropic Peptide

Beginner

An enhanced version of Selank with improved stability, studied for anxiety reduction and cognitive enhancement.

CognitiveAnxiolyticNootropic+1

EmergingModerate Data

Orexin-A

Neuropeptide

A neuropeptide that regulates wakefulness, arousal, and appetite. Its deficiency causes narcolepsy.

SleepCognitiveWakefulness+1

EmergingLimited Data

P21

Neurotrophic Peptide

A CNTF-derived peptide that promotes neurogenesis and has shown promise in Alzheimer's disease research.

CognitiveNeuroprotectiveNeurogenesis

PreliminaryLimited Data

Trofinetide

IGF-1 Tripeptide Analogue

The first FDA-approved treatment for Rett syndrome, a synthetic analogue of a naturally occurring IGF-1 tripeptide fragment.

FDA-ApprovedNeuroprotectiveRare Disease

StrongWell-Studied