Skip to content

Peptide Directory

Explore all 74 peptides with evidence ratings, safety profiles, and research-backed content.

A comprehensive directory of 74 peptides used in research and clinical practice — from recovery compounds like BPC-157 and TB-500 to GH secretagogues, neuropeptides, and GLP-1 receptor agonists. Each profile includes evidence ratings, safety data, mechanism of action, PubMed citations, and common use cases to help you understand the research behind each compound.

74 peptides found

BPC-157

Gastric Peptide

Beginner

A synthetic peptide derived from a protective protein found in gastric juice, widely discussed for tissue repair and recovery.

RecoveryGut HealthTissue Repair+2
EmergingModerate Data

Semaglutide

GLP-1 Receptor Agonist

Beginner

A GLP-1 receptor agonist FDA-approved for type 2 diabetes and chronic weight management, one of the most widely prescribed peptide drugs.

Weight LossMetabolic HealthFDA-Approved+1
StrongWell-Studied

Tirzepatide

Dual GIP/GLP-1 Receptor Agonist

Beginner

A dual GIP/GLP-1 receptor agonist FDA-approved for diabetes and weight management, producing the largest weight loss seen in clinical trials.

Weight LossMetabolic HealthFDA-Approved+2
StrongWell-Studied

CJC-1295

GHRH Analog

Beginner

A growth hormone-releasing hormone analog that stimulates the pituitary gland to produce more growth hormone.

Growth HormoneBody CompositionRecovery+2
ModerateModerate Data

Ipamorelin

Growth Hormone Secretagogue

Beginner

A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin.

Growth HormoneBody CompositionRecovery+2
ModerateModerate Data

NAD+ Precursors (NMN/NR)

Nucleotide/Vitamin B3 Derivative

Beginner

Precursors to NAD+, a critical coenzyme for cellular energy and longevity pathways. NAD+ levels decline with age.

LongevityAnti-AgingCellular Energy+1
ModerateWell-Studied

TB-500

Tissue Repair Peptide

Beginner

A synthetic version of the active region of thymosin beta-4, widely used for tissue repair, wound healing, and recovery from injuries.

RecoveryWound HealingAnti-Inflammatory+1
EmergingModerate Data

GHK-Cu

Copper Peptide

Beginner

A naturally occurring copper-binding peptide with extensive research on skin remodeling, wound healing, and anti-aging.

SkinAnti-AgingWound Healing+2
ModerateWell-Studied

Retatrutide

Triple GIP/GLP-1/Glucagon Receptor Agonist

An investigational triple agonist (GIP/GLP-1/glucagon) that produced 24% weight loss in Phase II trials, potentially the most effective obesity drug.

Weight LossInvestigationalGLP-1+2
EmergingModerate Data

Oxytocin

Neuropeptide Hormone

Beginner

A naturally occurring neuropeptide involved in social bonding, trust, and reproduction, FDA-approved for labor induction.

HormonalFDA-ApprovedSocial Bonding+1
StrongWell-Studied

Glutathione

Tripeptide Antioxidant

Beginner

The body's most abundant antioxidant, a tripeptide critical for detoxification, immune function, and cellular protection.

AntioxidantDetoxificationImmune+2
ModerateWell-Studied

Semax

Nootropic Peptide

Beginner

A synthetic peptide analog of ACTH(4-10) developed in Russia, studied for cognitive enhancement and neuroprotection.

Cognitive SupportNeuroprotectionFocus+1
EmergingModerate Data

Sermorelin

GHRH Analog

Beginner

A growth hormone-releasing hormone analog that was previously FDA-approved for diagnosing GH deficiency in children.

Growth HormoneAnti-AgingSleep+1
StrongWell-Studied

MK-677

Growth Hormone Secretagogue

An orally active growth hormone secretagogue that mimics ghrelin to stimulate GH and IGF-1 release.

Growth HormoneBody CompositionSleep+2
ModerateModerate Data

PT-141 (Bremelanotide)

Melanocortin Receptor Agonist

Beginner

An FDA-approved melanocortin receptor agonist for hypoactive sexual desire disorder in premenopausal women, also studied for broader sexual dysfunction.

Sexual WellnessFDA-ApprovedLibido+1
StrongWell-Studied

BPC-157 Arginate

Gastric Peptide

Beginner

A stabilized form of BPC-157 combined with arginine, offering enhanced stability and potentially improved oral bioavailability.

RecoveryGut HealthTissue Repair+2
PreliminaryLimited Data

CJC-1295 (no DAC)

GHRH Analog

Beginner

A modified growth hormone releasing hormone analog with a shorter half-life than DAC-conjugated CJC-1295, allowing more physiological GH pulsing.

Growth HormoneBody CompositionRecovery+1
ModerateModerate Data

Liraglutide

GLP-1 Receptor Agonist

Beginner

A GLP-1 receptor agonist FDA-approved for diabetes (Victoza) and weight management (Saxenda), the predecessor to semaglutide.

Weight LossMetabolic HealthFDA-Approved+1
StrongWell-Studied

Follistatin

Activin-Binding Protein

A naturally occurring protein that inhibits myostatin (the muscle growth limiter), studied for dramatic muscle growth potential.

Muscle GrowthMyostatin InhibitorPerformance
EmergingLimited Data

KPV

Anti-Inflammatory Tripeptide

Beginner

A tripeptide fragment of alpha-MSH with potent anti-inflammatory properties, studied for inflammatory bowel disease and skin conditions.

Anti-InflammatoryGut HealthSkin Health+1
EmergingLimited Data

Argireline

Cosmetic Peptide

Beginner

A cosmetic peptide that reduces wrinkles by inhibiting neurotransmitter release at the neuromuscular junction, often called 'topical Botox.'

Skin HealthAnti-AgingTopical+1
ModerateWell-Studied

Matrixyl

Signal Peptide (Cosmetic)

Beginner

A collagen-stimulating cosmetic peptide that signals skin to produce more collagen and extracellular matrix proteins.

Skin HealthAnti-AgingCollagen+1
ModerateWell-Studied

Cagrilintide

Amylin Analogue

A long-acting amylin analogue being developed in combination with semaglutide (CagriSema) for enhanced weight loss.

Weight LossMetabolic HealthInvestigational
EmergingModerate Data

Selank

Nootropic Peptide

Beginner

A synthetic peptide analog of tuftsin with anxiolytic and nootropic properties, developed in Russia.

AnxietyMoodCognitive Support+1
EmergingModerate Data

Tesamorelin

GHRH Analog

An FDA-approved GHRH analog used to reduce visceral fat in HIV-associated lipodystrophy.

Growth HormoneBody CompositionFat Loss+1
StrongWell-Studied

AOD-9604

GH Fragment

Beginner

A modified fragment of human growth hormone studied specifically for fat metabolism without the growth-promoting effects of full GH.

Fat LossBody CompositionMetabolic
EmergingModerate Data

FOXO4-DRI

Senolytic Peptide

A senolytic peptide designed to selectively clear senescent cells by disrupting the FOXO4-p53 interaction, studied for anti-aging applications.

LongevitySenolyticAnti-Aging+1
PreliminaryLimited Data

Cerebrolysin

Neurotrophic Peptide Complex

A porcine brain-derived peptide preparation with neurotrophic properties, approved in several countries for stroke recovery and cognitive disorders.

NeuroprotectionCognitive EnhancementStroke Recovery+1
StrongWell-Studied

GHR-2 (GHRP-2)

Growth Hormone Secretagogue

A synthetic growth hormone secretagogue that stimulates natural GH release, studied for body composition, recovery, and anti-aging.

Growth HormoneBody CompositionRecovery+1
ModerateModerate Data

Hexarelin

Growth Hormone Secretagogue

A potent growth hormone secretagogue peptide that also has cardioprotective properties independent of GH release.

Growth HormoneCardioprotectiveNeuroprotective+1
ModerateModerate Data

IGF-1 LR3

Growth Factor Analogue

A modified version of IGF-1 with extended half-life and reduced IGF binding protein affinity, used for muscle growth.

Growth FactorMuscle GrowthPerformance
EmergingLimited Data

N-Acetyl Selank Amidate

Nootropic Peptide

Beginner

An enhanced version of Selank with improved stability, studied for anxiety reduction and cognitive enhancement.

CognitiveAnxiolyticNootropic+1
EmergingModerate Data

Gonadorelin

Gonadotropin-Releasing Hormone

Synthetic gonadotropin-releasing hormone used diagnostically and therapeutically for reproductive hormone assessment and fertility.

HormonalFertilityDiagnostic+1
StrongWell-Studied

Melanotan II

Melanocortin Agonist

A synthetic melanocortin peptide studied for tanning, sexual function, and appetite suppression. Not FDA-approved; the FDA has issued public warnings against its use.

SkinSexual WellnessAppetite+1
EmergingUse Caution

Epithalon

Bioregulator Peptide

A synthetic tetrapeptide studied for its potential to activate telomerase and influence cellular aging.

LongevityAnti-AgingTelomeres+1
PreliminaryLimited Data

Thymosin Alpha-1

Thymic Peptide

A thymic peptide approved in multiple countries for immune modulation, particularly in hepatitis and as a vaccine adjuvant.

Immune SupportApproved InternationallyHepatitis+1
StrongWell-Studied

Humanin

Mitochondrial-Derived Peptide

A mitochondria-derived peptide with cytoprotective properties, studied for neuroprotection, metabolic regulation, and anti-aging effects.

NeuroprotectionLongevityMetabolic Health+1
EmergingLimited Data

VIP

Neuropeptide

A naturally occurring neuropeptide with anti-inflammatory, neuroprotective, and immune-modulating properties. Early clinical data exists for pulmonary hypertension; other therapeutic uses remain under investigation.

Anti-InflammatoryNeuroprotectionImmune Modulation+1
ModerateModerate Data

GHRP-6

Growth Hormone Secretagogue

A synthetic growth hormone secretagogue known for potent GH release and significant appetite stimulation through ghrelin receptor activation.

Growth HormoneAppetiteBody Composition+1
ModerateModerate Data

Larazotide

Tight Junction Regulator

Beginner

A synthetic peptide that regulates intestinal tight junctions, in clinical trials for celiac disease and studied for leaky gut conditions.

Gut HealthTight JunctionsCeliac Disease+1
ModerateWell-Studied

Exenatide

GLP-1 Receptor Agonist

Beginner

The first GLP-1 receptor agonist, originally derived from Gila monster venom, FDA-approved for type 2 diabetes.

Metabolic HealthFDA-ApprovedGLP-1
StrongWell-Studied

IGF-1 DES

Growth Factor Analogue

A truncated form of IGF-1 missing the first 3 amino acids, with 10x greater potency and very short half-life for localized effects.

Growth FactorMuscle GrowthPerformance
EmergingLimited Data

MGF

Growth Factor Splice Variant

A splice variant of IGF-1 produced in response to mechanical stress on muscles, promoting satellite cell activation and muscle repair.

Growth FactorMuscle GrowthRecovery
EmergingLimited Data

PEG-MGF

PEGylated Growth Factor

A PEGylated version of MGF with extended half-life for systemic muscle growth and recovery effects.

Growth FactorMuscle GrowthRecovery
PreliminaryLimited Data

Teriparatide

Parathyroid Hormone Fragment

An FDA-approved fragment of parathyroid hormone that stimulates new bone formation, used for severe osteoporosis.

Bone HealthFDA-ApprovedHormonal
StrongWell-Studied

Orexin-A

Neuropeptide

A neuropeptide that regulates wakefulness, arousal, and appetite. Its deficiency causes narcolepsy.

SleepCognitiveWakefulness+1
EmergingLimited Data

P21

Neurotrophic Peptide

A CNTF-derived peptide that promotes neurogenesis and has shown promise in Alzheimer's disease research.

CognitiveNeuroprotectiveNeurogenesis
PreliminaryLimited Data

Leuprolide

GnRH Agonist

An FDA-approved GnRH agonist used for prostate cancer, endometriosis, and precocious puberty through hormonal suppression.

FDA-ApprovedHormonalOncology+1
StrongWell-Studied

Glucagon

Peptide Hormone

Beginner

A naturally occurring peptide hormone that raises blood sugar, FDA-approved as emergency treatment for severe hypoglycemia.

FDA-ApprovedMetabolic HealthEmergency Medicine
StrongWell-Studied

N-Acetyl Epithalon Amidate

Bioregulator Peptide

An enhanced version of Epithalon with improved stability, studied for telomerase activation, pineal gland regulation, and anti-aging effects.

LongevityAnti-AgingTelomeres+2
PreliminaryLimited Data

Melanotan I

Melanocortin Agonist

An FDA-approved selective MC1R agonist for erythropoietic protoporphyria (EPP). Stimulates protective eumelanin production without the broad side effects of Melanotan II.

SkinPhotoprotectionFDA-Approved+2
StrongWell-Studied

LL-37

Antimicrobial Peptide

A naturally occurring antimicrobial peptide that plays a key role in innate immune defense.

Immune SupportAntimicrobialGut Health+1
EmergingLimited Data

Dihexa

Angiotensin Analog

A potent angiotensin IV analog studied for cognitive enhancement and potential treatment of neurodegenerative conditions.

Cognitive SupportNeuroprotectionMemory+1
PreliminaryLimited Data

DSIP

Neuropeptide

A naturally occurring neuropeptide that modulates sleep patterns and has been studied for insomnia and stress.

SleepStressMood+1
EmergingLimited Data

SNAP-8

Cosmetic Peptide

Beginner

A cosmetic peptide that reduces the appearance of wrinkles by modulating neuromuscular junction signaling.

SkinAnti-AgingWrinkles+2
EmergingWell-Studied

MOTS-c

Mitochondrial Peptide

A mitochondria-derived peptide that regulates metabolic homeostasis and has been called an 'exercise mimetic.'

MetabolicExerciseLongevity+1
EmergingLimited Data

Thymalin

Thymic Peptide

A thymic peptide complex studied for immune system restoration, particularly in aging populations and immunocompromised states.

Immune SupportLongevityAnti-Aging+1
ModerateModerate Data

PE-22-28

Neuroactive Peptide

A synthetic peptide derived from sortilin that acts as a TREK-1 channel blocker, studied as a rapid-acting antidepressant alternative.

MoodAntidepressantNeuroplasticity+1
PreliminaryLimited Data

Calcitonin (Salmon)

Peptide Hormone

Beginner

An FDA-approved peptide hormone used to treat osteoporosis and Paget's disease by inhibiting bone resorption.

Bone HealthFDA-ApprovedHormonal
StrongWell-Studied

Desmopressin

Vasopressin Analogue

Beginner

A synthetic analogue of vasopressin (ADH) FDA-approved for diabetes insipidus, bedwetting, and bleeding disorders.

HormonalFDA-ApprovedKidney
StrongWell-Studied

Pramlintide

Amylin Analogue

An FDA-approved synthetic analogue of amylin used alongside insulin for diabetes, also studied for weight management.

Metabolic HealthFDA-ApprovedWeight Loss+1
StrongWell-Studied

Setmelanotide

Melanocortin-4 Receptor Agonist

An FDA-approved MC4R agonist for rare genetic obesity disorders, representing a precision medicine approach to weight management.

Weight LossFDA-ApprovedGenetic Obesity+1
StrongWell-Studied

Octreotide

Somatostatin Analogue

An FDA-approved somatostatin analogue used to treat acromegaly, carcinoid tumors, and severe diarrhea.

FDA-ApprovedHormonalOncology
StrongWell-Studied

Glatiramer Acetate

Immunomodulatory Peptide Mixture

An FDA-approved immunomodulatory peptide mixture for relapsing-remitting multiple sclerosis (MS).

FDA-ApprovedImmuneAutoimmune+1
StrongWell-Studied

Pentosan Polysulfate

Polysaccharide

A semi-synthetic polysaccharide with FDA approval for interstitial cystitis, also studied for joint and cartilage health.

Joint HealthFDA-ApprovedCartilage+1
StrongWell-Studied

NA-Semax-Amidate

Nootropic Peptide

A chemically modified version of Semax designed for improved stability. No published clinical or preclinical data exists for this specific compound.

Cognitive SupportNeuroprotectionFocus+1
LimitedLimited Data

Kisspeptin

Neuropeptide

A naturally occurring neuropeptide that plays a central role in reproductive hormone regulation and fertility.

HormonalFertilityReproductive Health+1
ModerateModerate Data

SS-31

Mitochondrial Peptide

A mitochondria-targeted peptide in clinical trials for heart failure and mitochondrial diseases.

MitochondrialHeart HealthLongevity+1
EmergingModerate Data

Pinealon

Bioregulator Peptide

Beginner

A short tripeptide studied for neuroprotective and cognitive-enhancing properties, part of the Khavinson peptide bioregulator family.

NeuroprotectionCognitive EnhancementAnti-Aging+1
PreliminaryLimited Data

Thymulin

Thymic Peptide

A zinc-dependent thymic peptide involved in T-cell maturation, studied for immune restoration and anti-inflammatory applications.

Immune SupportAnti-InflammatoryThymic+1
EmergingModerate Data

Cortagen

Bioregulator Peptide

A synthetic peptide bioregulator targeting brain cortex function, studied for cognitive enhancement and neuroprotection in aging.

Cognitive EnhancementNeuroprotectionBioregulator+1
PreliminaryLimited Data

Difelikefalin

Peripheral Kappa Opioid Agonist

An FDA-approved peripheral kappa opioid receptor agonist for chronic kidney disease-associated itch, without CNS side effects.

FDA-ApprovedPainKidney+1
StrongWell-Studied

Teduglutide

GLP-2 Analogue

An FDA-approved GLP-2 analogue that promotes intestinal growth, used for short bowel syndrome.

FDA-ApprovedGut HealthIntestinal Growth
StrongWell-Studied

Trofinetide

IGF-1 Tripeptide Analogue

The first FDA-approved treatment for Rett syndrome, a synthetic analogue of a naturally occurring IGF-1 tripeptide fragment.

FDA-ApprovedNeuroprotectiveRare Disease
StrongWell-Studied