Peptide Stacks
Popular peptide combinations with evidence summaries, synergy mechanisms, and research citations.
Many peptides are used in combination to target complementary pathways — from the BPC-157 + TB-500 recovery stack to growth hormone secretagogue pairings and GLP-1 formulations with nutrient support. Each stack page explains why the peptides are combined, the proposed synergy mechanism, what the evidence actually shows, and important considerations for clinical use.
All Stacks
BPC-157 + TB-500 (The Wolverine Stack)
Known as the Wolverine Stack — the most popular peptide recovery combination. BPC-157 targets localized tissue repair while TB-500 provides systemic healing and anti-inflammatory support.
CJC-1295 + Ipamorelin (The GH Secretagogue Stack)
The classic growth hormone secretagogue stack — often called the GH stack or sleep stack. Combines GHRH signaling (CJC-1295) with selective ghrelin receptor activation (ipamorelin) to amplify the body's natural nighttime growth hormone pulse.
Semaglutide + B12 (Compounded Semaglutide)
The most commonly prescribed compounded semaglutide formulation for weight loss. Pairs GLP-1 therapy with vitamin B12 to address nutrient absorption concerns and support energy during caloric restriction. Often includes glycine.
PT-141 + Oxytocin (The Intimacy Stack)
Combines PT-141's central arousal signaling with oxytocin's bonding and emotional connection effects for a comprehensive approach to sexual wellness and intimacy.
BPC-157 + GHK-Cu (The Regeneration Stack)
Combines BPC-157's systemic tissue repair with GHK-Cu's collagen remodeling and skin rejuvenation for comprehensive recovery and regeneration support.
Sermorelin + Glycine (The Sleep & GH Stack)
Pairs sermorelin's growth hormone-releasing activity with glycine's sleep-enhancing and metabolic benefits for optimized nighttime GH release and recovery.
Semax + Selank (The Nootropic Stack)
The Russian nootropic peptide combination — Semax for cognitive enhancement and BDNF upregulation paired with Selank for anxiolytic effects and stress resilience.
Thymosin Alpha-1 + KPV (The Immune & Gut Stack)
Pairs systemic immune modulation (Thymosin Alpha-1) with targeted gut anti-inflammatory action (KPV) for comprehensive immune and gastrointestinal support.